Hemophilia A (Boxer type)

£40.00

Please enter pet name
Please enter dog's sex
Please enter dog's date of birth
Please select if dog is KC registered
Please enter Kennel Club Name
Please enter KC Registration Number
Petagenics works very closely with the UK Kennel Club, and as such, agree to send to the Kennel Club tests results of ALL Kennel Club registered dogs, irrelevant of status (clear, carrier, affected). You (the customer), hereby agree to Petagenics forwarding your dogs test results to the Kennel Club, should you object to your dogs results being included in the results sent to the Kennel Club, then you should indicate here.
Please enter Microchip number
Please select test type
Category: Breed Title:   Breed history and information:  

Description

Other Names:
Inheritance:
X-Linked Recessive
Mutation(s):
C>G
Affected Gene(s):
F8
Affected Breed(s):
Boxer

Common Symptoms

Hemophilia A (boxer type) is an inherited bleeding disorder affecting dogs. Hemophilia A (boxer type) is caused by a deficiency of coagulation factor VIII, which is an essential protein needed for normal blood clotting. Affected dogs may bruise easily, have frequent nosebleeds, bleed from the mouth when juvenile teeth are lost, and experience prolonged bleeding after surgery or trauma. Dogs may show signs of lameness or stiffness if bleeding occurs in the joints or muscle. Less often, the bleeding may be severe enough to cause death. Due to the variable severity of the disorder, affected dogs may not be identified until a surgery is performed or trauma occurs at which time excessive bleeding is noted. Veterinarians performing surgery on known affected dogs should have ready access to blood banked for transfusions.

References

  • Christopherson PW, Bacek LM, King KB, Boudreaux MK. Two novel missense mutations associated with hemophilia A in a family of boxers, and a German shepherd dog. Vet Clin Pathol. 2014 Sep;43(3):312-6. [PubMed: 25040606]